Holy Hydrogen – A Scientific Starter Guide to Molecular Hydrogen Therapy 


Molecular Hydrogen Therapy represents a new age in biological optimization, anti-aging, performance, and overall health. 


Why we invest in hydrogen research.

At Holy Hydrogen, we’re committed to sharing the benefits of molecular hydrogen therapy with as many people as possible. As we continue H2 research and development, we expect to discover more effective ways to produce and use hydrogen in therapeutic ways. To this point, we’ve developed a world-class hydrogen generator – the Lourdes Hydrofix Premium Edition –  that produces the most stable and pure therapeutic hydrogen. This is the only device in it’s price range that produces both hydrogen water and gas to inhale – while either individual method of hydrogen use is better than nothing, in order to maximize the benefits of hydrogen using the water and gas are both necessary. 


What you need to know about molecular hydrogen.

Pure molecular hydrogen is a medical-quality gas that consists of two hydrogen atoms bonded together. Most people hear that wonder what the difference is between H2 and H2O (water) – we’ll dive into this later but for now all you need to know is that the attached oxygen atom in regular water prevents the hydrogen from functioning as a selective antioxidant and relieving oxidative stress and inflammation.


Hydrogen – the foundation of life itself.

Hydrogen is among the most common and abundant molecules in our universe. As the smallest, most basic molecule in existence, many scientists believe molecular hydrogen to have played a pivotal role in the creation of our universe and everything in it. In fact, hydrogen served as the life force for basic cellular life forms called eukaryotes that began evolving about 2 billion years ago.

First, you need to understand how our bodies get messed up by free radicals and oxidative stress/inflammation. 

In order to understand how hydrogen impacts our bodies by relieving inflammation and oxidative stress, we need a basic understanding of free radicals and antioxidants as well.

Oxygen plays a necessary and yet potentially destructive role in life processes. 


Here’s a little chemistry lesson on oxygen and free radicals.

It may sound a little counter-intuitive, but oxygen is both necessary and potentially destructive. Oxygen (O2) is constantly splitting up and floating around with unpaired electrons until it “bumps into” another atom to bond with. Atoms like this with unpaired electrons are called “free radicals” and they play an important role in our bodies… but sometimes they get out of hand… 

Once they’re formed, free radicals can create a domino effect that destabilizes or destroys other molecules. They can damage cells, proteins, DNA etc. They can also change how cell membranes (walls around the cell) function and impact what molecules enter and leave cells. These problems are also known by the blanket term of “oxidative stress” that we’ll explain more in a few paragraphs.

In short, too many free radicals bouncing around our bodies is a recipe for disaster. Free radicals are linked by research to all sorts of human diseases including cancer, Alzheimer’s disease, Parkinson’s disease, atherosclerosis, and more. Many researchers believe that free radicals are linked to premature aging, some of them even have redefined aging as the “gradual accumulation of free radical damage.”

Eating unhealthy, processed, and sugary foods is correlated to an increase of free radicals. As are the medication we take, and even the water we drink. It’s not surprising that pesticides, alcohol, tobacco, and air pollutants also contribute to this.

But even things that are good for us can generate free radicals. For instance – breathing and exercise are correlated with free radicals because we breathe in oxygen and we put our bodies under physiological stress as we work out. But obviously, it’s still important to breathe and exercise. 


What does Oxidative Stress mean?  

When there are too many free radicals floating around damaging cells and physiological functions, we call that oxidative stress. Studies show that oxidative stress may impact the development of many health problems like cardiovascular/heart disease, certain cancers, arthritis, lupus, macular degeneration, emphysema, and more. Most of these also have significant crossover with chronic inflammation.


Why Are Antioxidants Important?

Antioxidants are a type of molecule that combats the free radicals in your body. We get antioxidants in two ways – our bodies naturally produce some but not enough to combat the damage that our bodies take so we also need to get antioxidants from what we consume. Plant based, whole foods, and antioxidant supplements like vitamin C and glutathione are excellent sources of antioxidants. 

Why antioxidant supplements can cause a problem…

At face value, a simple understanding of how antioxidants and free radicals work makes it seem like more antioxidants and less free radicals are better. But it’s not as simple as that. Because taking too many antioxidant supplements is actually correlated with a higher risk of disease in many instances. Supplemental antioxidants indiscriminately attack free radicals. But not ALL free radicals are bad – in fact, some of them in the right amounts are vital to keeping our cells healthy. They clean out parts of our bodies that need to be cleaned out – if we got rid of all free radicals, our bodies wouldn’t be able to recycle and restore.

So what does molecular hydrogen have to do with free radicals, oxidation, and inflammation?

Molecular hydrogen helps the body in a variety of ways, but most scientists group them into these three categories:

  1. Molecular Hydrogen is a selective antioxidant
  2. Molecular Hydrogen boosts your immune system
  3. Molecular Hydrogen improves cellular functions


First, hydrogen is a “selective antioxidant”

Hydrogen only scavenges the destructive and toxic free radicals/oxidants. Hydrogen seems to target the same free radicals that have been correlated with inflammation, chronic disease, DNA damage, and fatigue. It neutralizes the damaging free radicals while avoiding the free radicals that are helpful to our body’s processes. 

Molecular hydrogen seems to only reduce excessive oxidation that correlates with the destruction and damage of our cells.

Even more incredible than that, hydrogen can easily pass through any cell wall or membrane (including the blood brain barrier) to neutralize dangerous free radicals. Because it’s the smallest molecule in the universe, it can penetrate any cell wall and get inside any cell to deal with free radicals that larger antioxidants like vitamin C aren’t able to reach.​


Second, hydrogen boosts your immune system

Hydrogen activates the NRF2 pathway which, in simple terms, is the body’s natural defense network that fights free radicals. Without hydrogen, the body only activates this pathway when the body feels it is under attack – like when dealing with a toxin or an injury. 

Hydrogen naturally boosts the immune system and seems to prevent numerous diseases and conditions from gaining traction in the body.


Third, hydrogen improves cellular function

Hydrogen has been shown to help cells communicate with each other. It also down regulates the processes that lead to systemic inflammation. Hydrogen enhances mitochondrial function (how our cells produce energy) and protects cells from oxidative stress and degeneration. H2 has been found to increase the supply of mitochondria by activating a protein called PGC-1a which leads to an increase in cellular energy production. 

How to Get The Health Benefits of Molecular Hydrogen H2

Even though hydrogen is abundant in the universe, it’s rarely found in its pure molecular form on earth. This is why we engineered the Lourdes Hydrofix Premium Edition – to provide a simple way to ingest and breathe molecular hydrogen every day at home.

Holy Hydrogen’s Lourdes Hydrofix Premium Edition created consumable hydrogen in two ways – infusing H2 in water, and inhaling H2 with a nasal cannula. Doing either one will be beneficial, but in order to get the full benefits of hydrogen therapy, you need both. Breathing hydrogen through the nose sends hydrogen straight into the bloodstream and drinking hydrogen infused water sends hydrogen straight into the gut and digestive system – one is not better than the other, they just support your body in two different ways.




Research on Molecular Hydrogen

As of the writing of this article, over 1,000 peer-reviewed studies on hydrogen’s potential to impact human and animal disease models have been conducted and suggest that hydrogen has significant therapeutic potential. 

Hydrogen’s Scientific Origins

Hydrogen gas therapy has attracted the attention of scientific researchers since 2007, but research on the potential health benefits of hydrogen started much before that.

For example, Baylor University and Texas A&M scientists reported in the journal Science in 1975 that hyperbaric hydrogen treatment effectively reduced tumors in mice. 

Research has picked up since 2007 because a study on hydrogen gas’ therapeutic potential was published in Nature Medicine. The study by Dr. Ohta from Japan reported that inhaling 2%-4% molecular hydrogen gas had a significant positive impact in a rat model of ischemia-reperfusion recovery. They observed that hydrogen seemed to react with toxic free radicals, but didn’t react with other beneficial radical oxygen species such as nitric oxide, hydrogen peroxide, and superoxide.