Science Behind The Health Benefits of Molecular Hydrogen

Dr. Sunny Nason Episode 1 – Overview

Dr. Sunny Nason Episode 3 – Brain Health

Dr. Sunny Nason Episode 2 – Skin

Dr. Sunny Nason Episode 4 – The Starting Line of Health

Dr. Mark Sherwood – Hydrogen & Oxidative Stress Part 1

Dr. Mark Sherwood & Josh Trent – H2 Science: Stay Young Forever Via Natural Detox

Dr. Mark Sherwood – Hydrogen & Oxidative Stress Part 2

Luke Storey & Greg, the Hydrogen Man

Hydrogen Therapy with Dave Palumbo

Luke Storey & Dr. Mark Sherwood

“Holy” Hydrogen Overview

Testing The Lourdes Hydrofix Premium Edition Hydrogen Generator

Premium Edition vs 2018

Inhalation Testing

Why The Lourdes Hydrofix Premium Edition Is The Best Hydrogen Machine In The World


Because we care about the quality of hydrogen and the quality of your health, we’ve invested significant resources into creating better hydrogen production methods to improve your body’s ability to gain the benefits of hydrogen.  

The Lourdes Hydrofix is the only hydrogen machine that produces “structured hydrogen” that results in a more stable, longer lasting, higher saturated hydrogen water. “Super-nano Bubbles” of hydrogen make it easier for your body to utilize hydrogen. 

The Lourdes Hydrofix Premium Edition was developed based on Japan’s long-standing hydrogen research and Japan’s cutting-edge science and technology. We have properly tested and proved our product’s specs and we guarantee that our measurements are accurate. 


    • Most advanced Non-Electrolyzed Hydrogen Technology/Separate Chamber Electrolysis System
    • Highest grade Solid Polymer Electrolyte/Proton Exchange Membrane Technology
    • Latest NEMCA Effect* Technology (*Non-Faradaic Electrochemical Modification of Catalytic Activity)
    • State-of-the-art VIVE* Expanded Metal Technology (*Vortex Induced Vibration Engineering)

Non-Electrolyzed Hydrogen Technology/Separate Chamber Electrolysis System:

We developed a unique process to dissolve hydrogen into water in a stable, natural state in order to prevent the hydrogen from quickly escaping the water. This technology is called Separate Chamber Electrolysis and is the most advanced Non-Electrolyzed Hydrogen Technology in existence. Instead of directly electrolizing or force injecting hydrogen gas, the Lourdes Hydrofix dissolves hydrogen into the water in a natural way. That makes the hydrogen water more stable and long lasting.  The pH remains neutral as well (unlike the hydrogen tablets you may have seen on Amazon). The Lourdes Hydrofix Premium Edition produces the longest-lasting, most stable, pH neutral, non-toxic, natural hydrogen on the market.

SPE/PEM* Technology (*Solid Polymer Electrolyte/Proton Exchange Membrane): 

The Lourdes Hydrofix made SEP/PEM technology the standard in the hydrogen industry. Along with the complete Separate Chamber System, the Lourdes Hydrofix goes beyond basic SEP/PEM technologies. Unlike other hydrogen devices, the electrolysis process occurs underneath the pitcher in a completely separate place from the drinking water. This means that the drinking water is not directly electrolyzed but is still saturated with hydrogen because the membrane only allows hydrogen ions to pass through it. This makes hydrogen gas & water from the Lourdes Hydrofix the most pure for drinking and inhalation. The Lourdes Hydrofix only uses the highest grade membrane from Dupont. 

NEMCA Effect* Technology (*Non-Faradaic Electrochemical Modification of Catalytic Activity):

The Non-Faradaic Electrochemical Modification of Catalytic Activity (NEMCA) effect refers to the change in catalytic activity of an electrode that occurs in the absence of any redox processes or electron transfer reactions.

Japan leads the world in renewable energy research and technology. We, and other companies like Toyota, have been conducting research and technological development on the latest utilization of hydrogen energy and renewable energy. The latest technological advancements in Japan give us, “non-Faradaic conversion” that goes beyond conventional electric technology

Non-Faradaic Electrochemical Modification of Catalytic Activity (NEMCA effect*) is a method that does not follow Faraday’s law in electrochemical reactions, and obtains reactions higher than products derived by Faraday’s law with a lower electric current. This phenomenon is well documented and recognized as one of the most exciting discoveries in Electrochemistry which has a great impact on many catalytic and electrocatalytic processes. Japan’s latest NEMCA Effect* Technology (*Non-Faradaic Electrochemical Modification of Catalytic Activity) made it possible for us to achieve a higher production value of the hydrogen with less electricity. 

This produces savings in energy and a higher out-put of hydrogen gas.

NEMCA occurs when an applied potential bias modifies the electronic structure of the electrode surface, leading to changes in its catalytic activity. This effect has been observed for a wide range of electrochemical reactions, including the oxygen reduction reaction (ORR), hydrogen evolution reaction (HER), and CO oxidation reaction, among others.

The NEMCA effect can be exploited to design and optimize electrocatalysts for a variety of applications, including fuel cells, electrolyzers, and sensors. By modifying the electronic structure of the electrode surface, it is possible to enhance its catalytic activity, improve the selectivity of the reaction, and increase the stability of the catalyst.

Overall, the NEMCA effect represents an important phenomenon in electrochemistry that has significant implications for the design and optimization of electrocatalysts for a wide range of applications.

VIVE* (*Vortex Induced Vibration Engineering) Expanded Metal Technology:

The Lourdes Hydrofix uses state-of-the-art VIVE* Expanded Metal Technology (*Vortex Induced Vibration Engineering) from Japan to generate ultrafine super-nano hydrogen bubbles of hydrogen – smaller and more stable than any other naon bubbles in existence. Its unique patented design forces the nano hydrogen bubbles to move downstream inducing bubbles to vibrate and create powerful vortexes, generating the world’s first and only structured hydrogen water. Achieving a full saturation of longest-lasting stable hydrogen water that is more permeable and bioavailable.

Expand Metal vs Perforated/Punched Metal:

Perforated/Punched Metal is a very basic manufacturing method for the electrode and it is inferior in terms of durability, corrosion resistance and nano-ization of bubbles compared to the Expand Metal used for the Lourdes Hydrofix. 

Electrode Materials:

The Lourdes Hydrofix uses a Premium Expanded Metal electrode plate (made of pure titanium and pure platinum) instead of plated platinum (platinum coating) or a plated platinum colloid* which are commonly used on other hydrogen machines. (*The platinum colloid is a platinum processed with ethanol for industrial use and it is not the same as a colloidal platinum which is a food additive.) Almost all hydrogen products on the current market use cheaper metals to cut their costs. Many of the advanced technologies aren’t even available in China, Taiwan and Korea where inferior machines are manufactured. 

Plated metals used in other machines (both platinum colloid and base metal) erode much quicker when you run electricity through them – we’ve observed that it only takes 2-3 weeks of using plated metals before the machine starts leaching metals and chemicals into the water. In other words, plated metal is peeling off low quality base metals may be leaching into your drinking water. That can do more devastating harm to human than the benefits of molecular hydrogen, and that is why we did not make any compromise to the quality of the metal we use. This is why we only use pure medical grade platinum and titanium – because we care about your health more than we care about our margins. 

Non-Faradaic Electrochemical Modification of Catalytic Activity (NEMCA)

Non-Faradaic Electrochemical Modification of Catalytic Activity (NEMCA effect): https://en.wikipedia.org/wiki/Non-faradaic_electrochemical_modification_of_catalytic_activity

The Non-Faradaic Electrochemical Modification of Catalytic Activity (NEMCA) effect can have a significant impact on hydrogen gas production, which is a key application of electrocatalysis.

In the hydrogen evolution reaction (HER), protons (H+) are reduced to form hydrogen gas (H2) at the surface of the electrode. The efficiency of this process is strongly dependent on the activity and selectivity of the electrocatalyst used, which in turn can be modified by the NEMCA effect.

The NEMCA effect can modify the electronic structure of the electrode surface, leading to changes in its catalytic activity and selectivity for the HER. For example, it has been shown that applying a positive potential bias to a Pt electrode can enhance its HER activity by inducing the adsorption of H atoms on the surface, which are key intermediates in the reaction mechanism.

Similarly, the NEMCA effect can also affect the stability of the electrocatalyst, which is an important consideration for practical applications of hydrogen production. By modifying the electronic structure of the electrode surface, it is possible to enhance the resistance of the electrocatalyst to corrosion and other degradation mechanisms.

Overall, the NEMCA effect provides a powerful tool for optimizing the performance of electrocatalysts for hydrogen gas production, which has significant implications for the development of sustainable energy technologies.

Recent developments and trends in the electrochemical promotion of catalysis: https://link.springer.com/article/10.1007/s10800-009-9938-7

Faraday’s law of induction* is the law that the amount of electricity (unit C) that flows and the amount of substance that reacts is proportional https://en.wikipedia.org/wiki/Faraday%27s_law_of_induction. According to the law, the amount of electrons emitted from the current value can be derived, and the amount of product (hydrogen in this case) can be calculated from it. However, the calculation is only based on general electric technology and the hydrogen gas concentration depends not only on the size and quality of the electrode plate, but also on its technology, so it cannot be simply calculated from the voltage. The majority of the hydrogen products found on markets rely on very basic conventional electric technology that has not been improved for decades without much efforts put on development, and in that case, the amount of hydrogen calculated by this law could be equal to the actual result. In fact, in many cases it could be lesser due to reliability issues.

Holy Hydrogen – A Scientific Starter Guide to Molecular Hydrogen Therapy 


Molecular Hydrogen Therapy represents a new age in biological optimization, anti-aging, performance, and overall health. 


Why we invest in hydrogen research.

At Holy Hydrogen, we’re committed to sharing the benefits of molecular hydrogen therapy with as many people as possible. As we continue H2 research and development, we expect to discover more effective ways to produce and use hydrogen in therapeutic ways. To this point, we’ve developed a world-class hydrogen generator – the Lourdes Hydrofix Premium Edition –  that produces the most stable and pure therapeutic hydrogen. This is the only device in it’s price range that produces both hydrogen water and gas to inhale – while either individual method of hydrogen use is better than nothing, in order to maximize the benefits of hydrogen using the water and gas are both necessary. 


What you need to know about molecular hydrogen.

Pure molecular hydrogen is a medical-quality gas that consists of two hydrogen atoms bonded together. Most people hear that wonder what the difference is between H2 and H2O (water) – we’ll dive into this later but for now all you need to know is that the attached oxygen atom in regular water prevents the hydrogen from functioning as a selective antioxidant and relieving oxidative stress and inflammation.


Hydrogen – the foundation of life itself.

Hydrogen is among the most common and abundant molecules in our universe. As the smallest, most basic molecule in existence, many scientists believe molecular hydrogen to have played a pivotal role in the creation of our universe and everything in it. In fact, hydrogen served as the life force for basic cellular life forms called eukaryotes that began evolving about 2 billion years ago.

First, you need to understand how our bodies get messed up by free radicals and oxidative stress/inflammation. 

In order to understand how hydrogen impacts our bodies by relieving inflammation and oxidative stress, we need a basic understanding of free radicals and antioxidants as well.

Oxygen plays a necessary and yet potentially destructive role in life processes. 


Here’s a little chemistry lesson on oxygen and free radicals.

It may sound a little counter-intuitive, but oxygen is both necessary and potentially destructive. Oxygen (O2) is constantly splitting up and floating around with unpaired electrons until it “bumps into” another atom to bond with. Atoms like this with unpaired electrons are called “free radicals” and they play an important role in our bodies… but sometimes they get out of hand… 

Once they’re formed, free radicals can create a domino effect that destabilizes or destroys other molecules. They can damage cells, proteins, DNA etc. They can also change how cell membranes (walls around the cell) function and impact what molecules enter and leave cells. These problems are also known by the blanket term of “oxidative stress” that we’ll explain more in a few paragraphs.

In short, too many free radicals bouncing around our bodies is a recipe for disaster. Free radicals are linked by research to all sorts of human diseases including cancer, Alzheimer’s disease, Parkinson’s disease, atherosclerosis, and more. Many researchers believe that free radicals are linked to premature aging, some of them even have redefined aging as the “gradual accumulation of free radical damage.”

Eating unhealthy, processed, and sugary foods is correlated to an increase of free radicals. As are the medication we take, and even the water we drink. It’s not surprising that pesticides, alcohol, tobacco, and air pollutants also contribute to this.

But even things that are good for us can generate free radicals. For instance – breathing and exercise are correlated with free radicals because we breathe in oxygen and we put our bodies under physiological stress as we work out. But obviously, it’s still important to breathe and exercise. 


What does Oxidative Stress mean?  

When there are too many free radicals floating around damaging cells and physiological functions, we call that oxidative stress. Studies show that oxidative stress may impact the development of many health problems like cardiovascular/heart disease, certain cancers, arthritis, lupus, macular degeneration, emphysema, and more. Most of these also have significant crossover with chronic inflammation.


Why Are Antioxidants Important?

Antioxidants are a type of molecule that combats the free radicals in your body. We get antioxidants in two ways – our bodies naturally produce some but not enough to combat the damage that our bodies take so we also need to get antioxidants from what we consume. Plant based, whole foods, and antioxidant supplements like vitamin C and glutathione are excellent sources of antioxidants. 

Why antioxidant supplements can cause a problem…

At face value, a simple understanding of how antioxidants and free radicals work makes it seem like more antioxidants and less free radicals are better. But it’s not as simple as that. Because taking too many antioxidant supplements is actually correlated with a higher risk of disease in many instances. Supplemental antioxidants indiscriminately attack free radicals. But not ALL free radicals are bad – in fact, some of them in the right amounts are vital to keeping our cells healthy. They clean out parts of our bodies that need to be cleaned out – if we got rid of all free radicals, our bodies wouldn’t be able to recycle and restore.

So what does molecular hydrogen have to do with free radicals, oxidation, and inflammation?

Molecular hydrogen helps the body in a variety of ways, but most scientists group them into these three categories:

  1. Molecular Hydrogen is a selective antioxidant
  2. Molecular Hydrogen boosts your immune system
  3. Molecular Hydrogen improves cellular functions


First, hydrogen is a “selective antioxidant”

Hydrogen only scavenges the destructive and toxic free radicals/oxidants. Hydrogen seems to target the same free radicals that have been correlated with inflammation, chronic disease, DNA damage, and fatigue. It neutralizes the damaging free radicals while avoiding the free radicals that are helpful to our body’s processes. 

Molecular hydrogen seems to only reduce excessive oxidation that correlates with the destruction and damage of our cells.

Even more incredible than that, hydrogen can easily pass through any cell wall or membrane (including the blood brain barrier) to neutralize dangerous free radicals. Because it’s the smallest molecule in the universe, it can penetrate any cell wall and get inside any cell to deal with free radicals that larger antioxidants like vitamin C aren’t able to reach.​


Second, hydrogen boosts your immune system

Hydrogen activates the NRF2 pathway which, in simple terms, is the body’s natural defense network that fights free radicals. Without hydrogen, the body only activates this pathway when the body feels it is under attack – like when dealing with a toxin or an injury. 

Hydrogen naturally boosts the immune system and seems to prevent numerous diseases and conditions from gaining traction in the body.


Third, hydrogen improves cellular function

Hydrogen has been shown to help cells communicate with each other. It also down regulates the processes that lead to systemic inflammation. Hydrogen enhances mitochondrial function (how our cells produce energy) and protects cells from oxidative stress and degeneration. H2 has been found to increase the supply of mitochondria by activating a protein called PGC-1a which leads to an increase in cellular energy production. 

How to Get The Health Benefits of Molecular Hydrogen H2

Even though hydrogen is abundant in the universe, it’s rarely found in its pure molecular form on earth. This is why we engineered the Lourdes Hydrofix Premium Edition – to provide a simple way to ingest and breathe molecular hydrogen every day at home.

Holy Hydrogen’s Lourdes Hydrofix Premium Edition created consumable hydrogen in two ways – infusing H2 in water, and inhaling H2 with a nasal cannula. Doing either one will be beneficial, but in order to get the full benefits of hydrogen therapy, you need both. Breathing hydrogen through the nose sends hydrogen straight into the bloodstream and drinking hydrogen infused water sends hydrogen straight into the gut and digestive system – one is not better than the other, they just support your body in two different ways.




Research on Molecular Hydrogen

As of the writing of this article, over 1,000 peer-reviewed studies on hydrogen’s potential to impact human and animal disease models have been conducted and suggest that hydrogen has significant therapeutic potential. 

Hydrogen’s Scientific Origins

Hydrogen gas therapy has attracted the attention of scientific researchers since 2007, but research on the potential health benefits of hydrogen started much before that.

For example, Baylor University and Texas A&M scientists reported in the journal Science in 1975 that hyperbaric hydrogen treatment effectively reduced tumors in mice. 

Research has picked up since 2007 because a study on hydrogen gas’ therapeutic potential was published in Nature Medicine. The study by Dr. Ohta from Japan reported that inhaling 2%-4% molecular hydrogen gas had a significant positive impact in a rat model of ischemia-reperfusion recovery. They observed that hydrogen seemed to react with toxic free radicals, but didn’t react with other beneficial radical oxygen species such as nitric oxide, hydrogen peroxide, and superoxide.